“Whooping Cough” Wrongly Diagnosed, Treated In Thousands of People
Friday, August 31st, 2007A speedier but less accurate laboratory test for pertussis, commonly called “whooping cough,” is responsible for false-positive test results in thousands of individuals, according to a recent report from epidemiologists with the U.S. Centers for Disease Control (CDC). Many of those individuals received completely unnecessary pertussis treatment with antibiotics.Thousands of Mistaken Diagnoses
Whooping cough/pertussis is a highly contagious upper respiratory tract infection, spread by coughing or sneezing. Government health officials had estimated that the number of pertussis cases has tripled in the U.S. since 2001, but nearly half of the cases diagnosed since 2001 have now been called into question because of the unreliable nature of the lab test used.
Outbreaks of what was thought to be whooping cough were reported in Massachusetts, New Hampshire, and Tennessee. In early 2004, a baby in a Tennessee town was diagnosed with whooping cough by the speedy test, and nearly 1,500 area residents were offered or treated with antibiotics for whooping cough. However, the slower but more reliable whooping cough test revealed that only the baby had a truly positive result.
Hospital Staff Reduced
At a Lebanon, N.H. hospital, a lab worker was incorrectly diagnosed with whooping cough in March 2006, and nearly 1,000 hospital employees were then put on furlough in an effort to prevent the infection of hospital patients. About 100 of the employees were diagnosed with pertussis with the quick test, and the results were eventually found to be wrong. Hundreds of the employees underwent unnecessary treatment with antibiotics.
In October 2006, the quicker-but-less-accurate test diagnosed pertussis in a toddler at Children’s Hospital in Boston. Some three dozen hospital workers were tested and found to be positive too, but when the more reliable bacteria culture test was performed by the CDC, it was found that all of these positive results were incorrect.
Reliable Test Takes One Week
The more accurate test for pertussis requires a week or more for the growth of pertussis bacteria from a patient’s test sample. Health officials have sometimes not wanted to wait that long to take preventive action against a pertussis outbreak.
The CDC is initiating a study with the goals of improving and standardizing the tests used to diagnose pertussis. In the meantime, the “outbreaks” of whooping cough are well described by Dr. William Schaffner, chairman of Vanderbilt University’s department of preventive medicine, who said, “It’s been a roller coaster. ‘Whoa, look at this big outbreak! Whoa, it wasn’t really pertussis!’”